
Ass. Prof. Mariana Wohlfahrtová, MD, Ph.D.
(formerly Urbanová)
Ass. Prof.
Education and training:
1999-2006
Medical Faculty
Faculty of Medicine, Safarik University, Kosice, Slovakia
2006-2010
Resident in Nephrology
Department of Nephrology, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
2010-2012
Fellowship in Nephrology
Department of Nephrology, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
2012
Nephrology Board Exam
1st Medical Faculty Charles University in Prague, Czech Republic
2015
PhD
1st Medical Faculty Charles University in Prague, Czech Republic
Topic of PhD thesis: The prediction of early graft function development and rejection of transplant kidney
2015
The Board of Transplant Medicine Qualification
Board of Transplant Medicine, Brussels, Belgium
Transplant Medicine, Common trunk and kidney transplantation modules
2020
Associate professor of internal medicine
1st Medical Faculty Charles University in Prague, Czech Republic
Topic: Vascular rejection after kidney transplantation
Experience
2015- 2020
Nephrologist
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic
2015- 2016
Head of Transplant Outpatient Clinic
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic
2015- 2020
Deputy Head for Science and Research
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic
Aug- Oct 2013
Research fellow
Department of Nephrology and Hypertension, Transplant Center, Mayo Clinic Rochester, Minnesota, USA
2015- 2020
Lector of Nephrology
1st Faculty of Medicine and General Faculty Hospital, Prague, Czech Republic
Sept- Nov 2018
Visiting clinician
Department of Nephrology and Hypertension, University of Utah Salt Lake City, Utah, USA
2019-2020
Nephrologist, general practioner
Canadian Medical Care, Prague
2021- now
Nephrologist, general practioner
Concierge Medicine Europe, Praha
2021- now
General practioner
Prague- Uhříněves
Internship and further education
2006
ESH Educational Master Course on Hypertension and Cardiovascular Risk
European Society of Hypertension, Prague, Czech Republic
2007
Transplant Preceptorship Program
Großhadern Hospital
Munich, Germany
2007
Transplant 360
Erasmus Medical Center
Rotterdam, The Netherlands
2009
Statistics on Biomedical Research
European Center for Medical Informatics, Statistics and Epidemiology, Euromise Prague, Czech Republic
2009
English Language Course: Cambridge E.S.O.L. Examination
Certificate of Advanced English, level C1
2009, 2010
Hesperis Course
European Society for Organ Transplantation
Barcelona, Spain & Edinburgh, Scotland
2010
Summer School on Modern Methods in Biostatistics and Epidemiology
Harvard University, Karolinska Institutet
Treviso, Italy
2011
Introductory Course on Epidemiology
European Renal Association, European Dialysis and Transplant Association Salzburg, Austria
2014
Course for Reviewers to be
European Renal Association, European Dialysis and Transplant Association Leiden, The Netherlands
Scientific and research activities
2015-2018
Grant of Ministry of Health of the Czech Republic
Vascular rejection phenotype after kidney transplantation and isolated v-lesion Principal investigator.
2017- present
Grant of Ministry of Health of the Czech Republic
Genetic variability of BKV in the Czech Republic and its influence on pathogenesis of infection in kidney transplant recipients
Subinvestigator
Awards
2011
2012
2012
2012
2013
2015
2020
2022
Scientific books and chapters
M. Wohlfahrtová, O. Viklický, R. Lischke. Transplantace orgánů v klinické praxi, Grada 2021
Wohlfahrtová M. Transplantační imunologie. In: Molitor M et al. Transplantace v rekonstrukční chirurgii. 1. vydání. Praha: Grada, 2017.
Urbanová M. Diabetes mellitus po transplantaci ledviny. In: VIKLICKÝ O, ADAMEC M, BALÁŽ P. a kol. Transplantace ledviny v klinické praxi. Grada 2008.
Urbanova M. Hematologické komplikace po transplantaci ledviny. In: VIKLICKÝ O, ADAMEC M, BALÁŽ P. a kol. Transplantace ledviny v klinické praxi. Grada 2008.
Recent international publications
Salakova M, Ludvikova V, Hamsikova V, Kolariova M, Sroller V, Viklicky O, and Wohlfahrtova M.
Pretransplantation seroreactivity in kidney donors and recipients as a predictive factor for posttransplant BKPyV viremia. Front. Immunol. in press
Hruba P, Krejcik Z, Stranecky V, Maluskova J, Slatinska J, Gueler F, Gwinner W, Brasen JH, Wohlfahrtova M, Parikova A, Osickova K, Fronek J, Seda O, Prefertusova L, Honsova E, Viklicky O. Molecular patterns discriminate accommodation and subclinical antibody-mediated rejection in kidney transplantation. Transplantatation 2019, accepted for publication
Wohlfahrtova M, Hruba P, Klema J, Novotny M, Krejcik Z, Stranecky V, Honsova E, Vichova P, Viklicky O. Early isolated V-lesion may not truly represent rejection of the kidney allograft. Clin Sci. 2018;132(20):2269-84.
Novotny M, Hruba P, Vichova P, Maluskova J, Honsova E, Viklicky O, Wohlfahrtova M. Isolated v-lesion resents a benign phenotype of vascular rejection of the kidney allograft – a retrospective study. Transpl Int. 2018;31(10):1153-63.
Wohlfahrtova M, Viklicky O. New strategies for evaluating the quality of kidney grafts from elderly donors. Transplant Rev 2015; 29: 212-8.
Wohlfahrtova M, Tycova I, Honsova E, Lodererova A, Viklicky O. Molecular Patterns of Subclinical and Clinical Rejection of Kidney Allograft: Quantity Matters. Kidney Blood Press Res 2015; 40:244-257.
Wohlfahrtova M, Viklicky O. Recent trials in immunosuppression and their consequences for current therapy. Curr Opin Organ Transplant. 2014 Aug;19(4):387-94.
Keddis MT, El Ters M, Rodrigo E, Dean P, Wohlfahrtova M, Kudva YC, Lorenz EC, Cosio FG. Enhanced posttransplant management of patients with diabetes improves patient outcomes. Kidney Int. 2014 Sep;86(3):610-8.
Balaz P, Rokosny S, Wohlfahrt P, Wohlfahrtova M, Adamec M, Janousek L, Fronek J, Viklicky O, Pokorna E. Dual kidney transplant: a single-center experience and review of the literature.
Exp Clin Transplant. 2013 Oct;11(5):388-95.
Wohlfahrtova M, Brabcova I, Zelezny F, Balaz P, Janousek L, Honsova E, Lodererova A, Wohlfahrt P, Viklicky O. Tubular atrophy and low netrin-1 gene expression are associated with delayed kidney allograft function. Transplantation 2014 Jan 27;97(2):176-83.
Balaz P, Rokosny S, Wohlfahrtova M, Wohlfahrt P, Bartonova A, Pokorna E, Honsova E, and Viklicky O. Identification of Expanded Criteria Donor Kidney Grafts at Lower Risk of Delayed Graft Function. Transplantation 2013 Oct 15;96(7):633-8.
Slatinska J, Rohal T, Wohlfahrtova M, and Viklicky O. Long-term Follow-up of Stable Kidney Transplant Recipients After Conversion From Tacrolimus Twice Daily Immediate Release to Tacrolimus Once-daily Prolonged Release: A Large Single-Center Experience. Transplant Proc. 2013 May;45(4):1491-6.
Urbanova M, Brabcova I, Girmanova E, Zelezny F, Viklicky O. Differential regulation of the nuclear factor-κB pathway by rabbit antithymocyte globulins in kidney transplantation. Transplantation 2012 Mar 27;93(6): 589-96.
Girmanova E, Brabcova I, Klema J, Hribova P, Wohlfartova M, Skibova J, Viklicky O. Molecular networks involved in the immune control of BK polyomavirus. Clin Dev Immunol, 2012.
Viklicky O, Krystufkova E, Brabcova I, Sekerkova A, Wohlfahrt P, Hribova P, Wohlfahrtova M, Sawitzki B, Slatinska J, Striz I, Volk HD, Reinke P. B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients. Transplantation 2013 Jan 15;95(1):148-5.
Viklicky O, Netuka I, Urbanova M, Adamec M, Maly J, Voska L, Pokorna E. Kidney Transplantation from a Brain-dead Heart Transplant Candidate Treated with Biventricular Assist Device: 12-Month Follow-up. NDT plus, 2008; 1(1):34-35.
Urbanova M, Kalousova M, Zima T, Skibova J, Wohlfahrt P, and Viklicky O. Fetuin-A Early after Renal Transplantation. Kidney Blood Press Res. 2009; 32(3):217-22.
Recent czech publications:
Wohlfahrtová, M. Jaké příznaky by měly praktického lékaře upozornit na renální onemocnění, kdy odeslat pacienta ke specialistovi. Practicus 2016;15(3):13-17. ISSN: 1213-8711.
Novotný M, Wohlfahrtová M, Viklický O. Pokroky v diagnostice a léčbě komplexu tuberózní sklerózy. Postgraduální medicína 2015;17(5): 472-477.
Wohlfahrtová, M, Černoch, M, Viklický O. Stárnoucí dárce ledviny k transplantaci. Postgraduální medicína 2015;17(5):563-569.
Řepová B., Wohlfahrtová M, Viklický O. Těhotenství po transplantaci ledviny nepředstavuje riziko pro ztrátu štěpu. Aktuality v nefrologii, 2013; 11(1), 78-81.
Viklický O, Slatinská J, Bürgelová M, Vítko S, Urbanová M, Lazanská R, Hanzal V, Bandúr S, Teplan V, Matl I, Janousek L, Honsová E, Drastichová M, Malý J. Kidney transplantation at the Institute for Clinical and Experimental Medicine. Cas Lek Cesk. 2011;150(1):56-9.
Mraz M, Urbanova M, Wohlfahrt P, Podracka L. The Brain Natriuretic Peptide (BNP) and Cardiovascular Risk in Pediatric Population (Mozgový nátriuretický peptid (BNP) a kardiovaskulárne riziko v detskom veku). Čes.-slov. Pediat. 2006;61(2): 89-94.
Professional Affiliations
- Founder and President of Young Transplantologist Platform at SOT, 2015-2017
- Czech Society of Nephrology, member
- Czech Medical Association, member
- Sdružení praktických lékařů ČR, member
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