Ass. Prof. Mariana Wohlfahrtová, MD, Ph.D.

GENERAL PRACTITIONER, NEPHROLOGY, INTERNIST

(formerly Urbanova)

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Personal Information

Date of birth

Medical Employment

2021 – PRESENT

General Practioner, Nephrologist
Concierge Medicine Europe, Praha

2021 – 2022

General Practioner
Prague – Uhříněves

2019 – 2020

Nephrologist, General Practioner
Canadian Medical Care, Prague

2018

Visiting Clinician
Department of Nephrology and Hypertension, University of Utah
Salt Lake City, Utah, USA

2015 – 2020

Lecturer of Nephrology
1st Faculty of Medicine Charles University and General Faculty Hospital, Prague, Czech Republic

2015 – 2020

Deputy Head for Science and Research
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic

2015 – 2016

Head of Transplant Outpatient Clinic
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic

2012 – 2020

Nephrologist
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic

2013

Research Fellow
Department of Nephrology and Hypertension, Transplant Center, Mayo Clinic
Rochester, Minnesota, USA

2010 – 2012

Fellowship in Nephrology
Department of Nephrology, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

2006 – 2010

Residency in Internal Medicine
Department of Nephrology, Transplant Center, IKEM, Prague, Czech Republic

Education And Qualifications

2022

General Practioner Board Exam
Institut for Postgradual Education, Prague, Czech Republic

2020

Associate Professor of Internal Medicine
1st Medical Faculty Charles University in Prague, Czech Republic
Topic: Vascular rejection after kidney transplantation

2015

PhD
1st Medical Faculty Charles University in Prague, Czech Republic
Topic of PhD thesis: The prediction of early graft function development and rejection of transplant kidney

2012

Nephrology Board Exam
1st Medical Faculty Charles University in Prague, Czech Republic

2010

Internal Medicine Trunk
Institut for Postgradual Education, Prague, Czech Republic

1999 – 2006

Medical Faculty
Faculty of Medicine, Safarik University, Kosice, Slovakia

Courses, Meetings, Conferences

2014

Course for Reviewers to be
European Renal Association, European Dialysis and Transplant Association
Leiden, The Netherlands

2011

Introductory Course on Epidemiology
European Renal Association, European Dialysis and Transplant Association
Salzburg, Austria

2010

Summer School on Modern Methods in Biostatistics and Epidemiology
Harvard University, Karolinska Institutet
Treviso, Italy

2009, 2010

Hesperis Course
European Society for Organ Transplantation
Barcelona, Spain & Edinburgh, Scotland

2009

English Language Course: Cambridge E.S.O.L. Examination
Certificate of Advanced English, level C1

2009

Statistics on Biomedical Research
European Center for Medical Informatics, Statistics and Epidemiology, Euromise
Prague, Czech Republic

2007

Transplant 360
Erasmus Medical Center
Rotterdam, The Netherlands

2007

Transplant Preceptorship Program
Großhadern Hospital
Munich, Germany

2006

ESH Educational Master Course on Hypertension and Cardiovascular Risk
European Society of Hypertension, Prague, Czech Republic

Scientific and research activities

2017 – 2020

Grant of Ministry of Health of the Czech Republic
Genetic variability of BKV in the Czech Republic and its influence on pathogenesis of infection in kidney transplant recipients
Subinvestigator

2015 – 2018

Grant of Ministry of Health of the Czech Republic
Vascular Rejection Phenotype after Kidney Transplantation and Isolated V-lesion
Principal investigator

Valuation

2022

Best Scientific Monography Award of Czech Society of Nephrology

2020

Czech Society of Nephrology Best scientific publication award

2015

Czech Health Ministry Award for Research and Progress

2013

ERA – EDTA Travel Grant, ERA – EDTA Congress 2013 Istanbul

2012

Czech Society of Nephrology Best Young Author Oral Presentation Award, Congress of Czech Society of Nephrology

2012

European Renal Association – European Dialysis Transplantation Association Best Young Author Abstract, ERA – EDTA Congress 2012 Paris

2011

Czech Transplantation Society, Travel Grant, ATC Philadelphia 2011

Publications

Wohlfahrtová M, Viklický O, Lischke R. Transplantace orgánů v klinické praxi, Grada 2021. ISBN: 978-80-271-0721-6.

Wohlfahrtová M. Transplantační imunologie. In: Molitor M et al. Transplantace v rekonstrukční chirurgii. 1. vydání. Praha: Grada, 2017.

Urbanová M. Diabetes mellitus po transplantaci ledviny. In: Viklický O, Adamec M, Baláž P. a kol. Transplantace ledviny v klinické praxi. Grada 2008.

Urbanová M. Hematologické komplikace po transplantaci ledviny. In Viklický O, Adamec M, Baláž P. a kol. Transplantace ledviny v klinické praxi. Grada 2008.

Salakova M, Ludvikova V, Hamsikova V, Kolariova M, Sroller V, Viklicky O, and Wohlfahrtova M.
Pretransplantation seroreactivity in kidney donors and recipients as a predictive factor for posttransplant BKPyV viremia. Front. Immunol. 2022 Jul 251(13):929-946.

Hruba P, Krejcik Z, Stranecky V, Maluskova J, Slatinska J, Gueler F, Gwinner W, Brasen JH, Wohlfahrtova M, Parikova A, Osickova K, Fronek J, Seda O, Prefertusova L, Honsova E, Viklicky O. Molecular patterns discriminate accommodation and subclinical antibody-mediated rejection in kidney transplantation. Transplantatation 2019, accepted for publication

Wohlfahrtova M, Hruba P, Klema J, Novotny M, Krejcik Z, Stranecky V, Honsova E, Vichova P, Viklicky O. Early isolated V-lesion may not truly represent rejection of the kidney allograft. Clin Sci. 2018 132(20):2269-84.

Novotny M, Hruba P, Vichova P, Maluskova J, Honsova E, Viklicky O, Wohlfahrtova M. Isolated v-lesion resents a benign phenotype of vascular rejection of the kidney allograft – a retrospective study. Transpl Int. 2018 31(10):1153-63.

Wohlfahrtova M, Viklicky O. New strategies for evaluating the quality of kidney grafts from elderly donors. Transplant Rev 2015 29: 212-8.

Wohlfahrtova M, Tycova I, Honsova E, Lodererova A, Viklicky O. Molecular Patterns of Subclinical and Clinical Rejection of Kidney Allograft: Quantity Matters. Kidney Blood Press Res 2015 40:244-257.

Wohlfahrtova M, Viklicky O. Recent trials in immunosuppression and their consequences for current therapy. Curr Opin Organ Transplant. 2014 Aug 19(4):387-94.

Keddis MT, El Ters M, Rodrigo E, Dean P, Wohlfahrtova M, Kudva YC, Lorenz EC, Cosio FG. Enhanced posttransplant management of patients with diabetes improves patient outcomes. Kidney Int. 2014 Sep 86(3):610-8.

Balaz P, Rokosny S, Wohlfahrt P, Wohlfahrtova M, Adamec M, Janousek L, Fronek J, Viklicky O, Pokorna E. Dual kidney transplant: a single-center experience and review of the literature.
Exp Clin Transplant. 2013 Oct 11(5):388-95.

Wohlfahrtova M, Brabcova I, Zelezny F, Balaz P, Janousek L, Honsova E, Lodererova A, Wohlfahrt P, Viklicky O. Tubular atrophy and low netrin-1 gene expression are associated with delayed kidney allograft function. Transplantation 2014 Jan 27 97(2):176-83.

Balaz P, Rokosny S, Wohlfahrtova M, Wohlfahrt P, Bartonova A, Pokorna E, Honsova E, and Viklicky O. Identification of Expanded Criteria Donor Kidney Grafts at Lower Risk of Delayed Graft Function. Transplantation 2013 Oct 15 96(7):633-8.

Slatinska J, Rohal T, Wohlfahrtova M, and Viklicky O. Long-term Follow-up of Stable Kidney Transplant Recipients After Conversion From Tacrolimus Twice Daily Immediate Release to Tacrolimus Once-daily Prolonged Release: A Large Single-Center Experience. Transplant Proc. 2013 May 45(4):1491-6.

Urbanova M, Brabcova I, Girmanova E, Zelezny F, Viklicky O. Differential regulation of the nuclear factor-κB pathway by rabbit antithymocyte globulins in kidney transplantation. Transplantation 2012 Mar 27 93(6): 589-96.

Girmanova E, Brabcova I, Klema J, Hribova P, Wohlfartova M, Skibova J, Viklicky O. Molecular networks involved in the immune control of BK polyomavirus. Clin Dev Immunol, 2012.

Viklicky O, Krystufkova E, Brabcova I, Sekerkova A, Wohlfahrt P, Hribova P, Wohlfahrtova M, Sawitzki B, Slatinska J, Striz I, Volk HD, Reinke P. B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients. Transplantation 2013 Jan 15 95(1):148-5.

Viklicky O, Netuka I, Urbanova M, Adamec M, Maly J, Voska L, Pokorna E. Kidney Transplantation from a Brain-dead Heart Transplant Candidate Treated with Biventricular Assist Device: 12-Month Follow-up. NDT plus, 2008 1(1):34-35.

Urbanova M, Kalousova M, Zima T, Skibova J, Wohlfahrt P, and Viklicky O. Fetuin-A Early after Renal Transplantation. Kidney Blood Press Res. 2009 32(3):217-22.

Wohlfahrtová, M. Jaké příznaky by měly praktického lékaře upozornit na renální onemocnění, kdy odeslat pacienta ke specialistovi. Practicus 2016 15(3):13-17. ISSN: 1213-8711.

Novotný M, Wohlfahrtová M, Viklický O. Pokroky v diagnostice a léčbě komplexu tuberózní sklerózy. Postgraduální medicína 2015 17(5): 472-477.

Wohlfahrtová, M, Černoch, M, Viklický O. Stárnoucí dárce ledviny k transplantaci. Postgraduální medicína 2015 17(5):563-569.

Řepová B., Wohlfahrtová M, Viklický O. Těhotenství po transplantaci ledviny nepředstavuje riziko pro ztrátu štěpu. Aktuality v nefrologii, 2013 11(1), 78-81.

Viklický O, Slatinská J, Bürgelová M, Vítko S, Urbanová M, Lazanská R, Hanzal V, Bandúr S, Teplan V, Matl I, Janousek L, Honsová E, Drastichová M, Malý J. Kidney transplantation at the Institute for Clinical and Experimental Medicine. Cas Lek Cesk. 2011 150(1):56-9.

Mraz M, Urbanova M, Wohlfahrt P, Podracka L. The Brain Natriuretic Peptide (BNP) and Cardiovascular Risk in Pediatric Population (Mozgový nátriuretický peptid (BNP) a kardiovaskulárne riziko v detskom veku). Čes.-slov. Pediat. 2006 61(2): 89-94.

Membership In Medical Societies

Founder and President of Young Transplantologist Platform at SOT, 2015-2017

Czech Medical Association, member

Sdružení praktických lékařů ČR, member

Společnost všeobecného lékařství (Association of General Practioners), Czech Republic, member

Peer reviewer of scientific manuscripts (Transplant International)